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WHAT IS LGMD
Limb girdle muscular dystrophy is a group of inherited disorders that progressively affects the pelvic and shoulder girdles making them weak and waste away. LGMDs are rare conditions and they present differently in people.
The muscles that are affected are the proximal muscles these muscles are closest to the body.
LGMD is caused by a mutation in any of at least 15 genes that affect proteins necessary for muscle function.
There are also more than 20 subtypes of LGMD and they are divided into two. We have autosomal dominant where LGMD is inherited from one parent and autosomal recessive where the faulty gene is inherited from both parents.
The severity, age of onset and features of limb-girdle muscular dystrophy vary among the many subtypes and even within the same family individuals show inconsistency in severity.
